Dr. Thomas Klein is a board-certified clinical hematologist serving as Chief Medical Officer at Kantesti AI. With over 15 years of experience in laboratory medicine and a strong interest in AI-supported interpretation of blood test results, he works to connect new technology with everyday clinical practice. His areas of interest include biomarker analysis, clinical decision support research and population-specific reference range optimization. As CMO, he contributes clinical input to the platform's internal benchmarking and provides clinical oversight for the medical quality of Kantesti's educational reports.

MTHFR Test Results: Variant Meaning and Real Next Steps

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Genetics Explained Lab Interpretation 2026 Update Patient-Friendly Common MTHFR variants are genetic findings, not diagnoses. The useful next step is usually checking folate, vitamin B12 and—only in the right clinical setting—homocysteine rather than treating a genotype. 📖 ~10-12 minutes 📅 September 18, 2026 📝 Published: September 18, 2026 🩺 Medically Reviewed: September 18, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. Thomas Klein is a board-certified clinical […]

Burr Cells on a Blood Smear: Kidney and Artifact Clues

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Peripheral Smear Lab Interpretation 2026 Update Patient-Friendly Burr cells, also called echinocytes, are often created after the sample leaves the body. Persistent, well-distributed findings can still provide a useful prompt to review renal function, electrolytes, and the wider clinical picture. 📖 ~11 minutes 📅 September 18, 2026 📝 Published: September 18, 2026 🩺 Medically Reviewed: September 18, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. Thomas Klein […]

High Glucose Symptoms: Thirst, Vision Changes and Red Flags

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Diabetes Symptoms Lab Interpretation 2026 Update Patient-Friendly Excessive thirst and blurred vision can signal elevated glucose, but vomiting, deep breathing, confusion, or ketones change the urgency. Here is how clinicians separate a prompt appointment from emergency assessment. 📖 ~11 minutes 📅 September 18, 2026 📝 Published: September 18, 2026 🩺 Medically Reviewed: September 18, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. Thomas Klein is a board-certified […]

Duffy-Null Neutrophil Count: When Low ANC Is Normal

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Hematology Lab Interpretation 2026 Update Patient-Friendly A persistently low ANC can be normal when it reflects Duffy-null associated neutrophil count (DANC), especially if you are well and other blood-cell lines are normal. The key is confirming a stable pattern while not dismissing new symptoms, fever, or changes in hemoglobin and platelets. 📖 ~11 minutes 📅 September 18, 2026 📝 Published: September 18, 2026 🩺 Medically Reviewed: September 18, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author […]

Positive Antibody Screen in Pregnancy: Your Next Steps

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Pregnancy Blood Tests Lab Interpretation 2026 Update Patient-Friendly A positive red-cell antibody result tells your maternity team to identify the antibody and measure its significance. Many results never harm a baby, but a small group need carefully timed specialist monitoring. 📖 ~11 minutes 📅 September 18, 2026 📝 Published: September 18, 2026 🩺 Medically Reviewed: September 18, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. Thomas Klein […]

Beta-Hydroxybutyrate Levels: Ketosis vs Ketoacidosis

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Ketone Testing Lab Interpretation 2026 Update Patient-Friendly A raised blood ketone result can be a normal fuel response or an early warning of diabetic ketoacidosis. The number matters, but glucose, bicarbonate, symptoms and medicines decide the risk. 📖 ~11 minutes 📅 September 17, 2026 📝 Published: September 17, 2026 🩺 Medically Reviewed: September 17, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. Thomas Klein is a board-certified […]

Absolute Monocyte Count vs Percentage: Which Matters?

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CBC Differential Lab Interpretation 2026 Update Patient-Friendly A monocyte percentage can look high simply because other white cells are low. The absolute count shows how many monocytes are actually circulating and usually gives the more useful clinical context. 📖 ~11 minutes 📅 September 17, 2026 📝 Published: September 17, 2026 🩺 Medically Reviewed: September 17, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. Thomas Klein is a […]

What Does LDH Stand For? Test Meaning and Follow-Up

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Lab Acronym Guide Lab Interpretation 2026 Update Patient-Friendly LDH is a useful clue to cell stress or cell breakdown, not a diagnosis. The number becomes meaningful only when it is read beside your symptoms, sample quality, CBC, liver tests, and recent activity. 📖 ~11 minutes 📅 September 17, 2026 📝 Published: September 17, 2026 🩺 Medically Reviewed: September 17, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. […]

CA 27-29 Test Results: Uses, Ranges and Limits

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Breast Cancer Follow-Up Lab Interpretation 2026 Update Patient-Friendly CA 27-29 is a MUC1-related tumour marker used selectively to follow some people with known metastatic breast cancer. A high result alone does not diagnose cancer, and the pattern over time matters far more than one number. 📖 ~11 minutes 📅 September 17, 2026 📝 Published: September 17, 2026 🩺 Medically Reviewed: September 17, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, […]

Blood Tests for Frequent Infections: What to Check First

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Immune Health Lab Interpretation 2026 Update Patient-Friendly Most adults with several colds a year do not have an immune disorder. This symptom-led pathway shows when basic blood work is enough, when targeted immune testing makes sense, and when prompt medical review matters. 📖 ~11 minutes 📅 September 17, 2026 📝 Published: September 17, 2026 🩺 Medically Reviewed: September 17, 2026 ✅ Evidence-Based This guide was written under the leadership of Dr. Thomas Klein, MD in collaboration with the Kantesti AI Medical Advisory Board, including contributions from Prof. Dr. Hans Weber and medical review by Dr. Sarah Mitchell, MD, PhD. Lead Author Thomas Klein, MD Chief Medical Officer, Kantesti AI Dr. […]